N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: Application to Sansalvamide A peptide analogs

Ana I. Fernández-Llamazares; Jesús García; Vanessa Soto-Cerrato; Ricardo Pérez-Tomás; Jan Spengler; Fernando Albericio

doi:10.1039/c3cc41788c

N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: Application to Sansalvamide A peptide analogs

Ana I. Fernández-Llamazares
, Jesús García
, Vanessa Soto-Cerrato
, Ricardo Pérez-Tomás
, Jan Spengler
, Fernando Albericio

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

17 Citas (Scopus)

Resumen

Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared.

Idioma original	Inglés
Páginas (desde-hasta)	6430-6432
Número de páginas	3
Publicación	Chemical Communications
Volumen	49
N.º	57
DOI	https://doi.org/10.1039/c3cc41788c
Estado	Publicada - 20 jun. 2013
Publicado de forma externa	Sí

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abstract = "Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared.",

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T2 - Application to Sansalvamide A peptide analogs

AU - Fernández-Llamazares, Ana I.

AU - García, Jesús

AU - Soto-Cerrato, Vanessa

AU - Pérez-Tomás, Ricardo

AU - Spengler, Jan

AU - Albericio, Fernando

PY - 2013/6/20

Y1 - 2013/6/20

N2 - Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared.

AB - Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared.

UR - https://www.scopus.com/pages/publications/84880869061

U2 - 10.1039/c3cc41788c

DO - 10.1039/c3cc41788c

M3 - Artículo

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SN - 1359-7345

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JO - Chemical Communications

JF - Chemical Communications

IS - 57

ER -

N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: Application to Sansalvamide A peptide analogs

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