Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Christoph Böttcher; Jan Spengler; Klaus Burger

doi:10.1007/s00706-004-0187-5

Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Christoph Böttcher
, Jan Spengler
, Klaus Burger

Leipzig University

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

3 Citas (Scopus)

Resumen

Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac ₄-β-D-Glc-NH₂/Bzl₄-β-D-Glc-NH ₂ using hexafluoroacetone as protecting and activating reagent.

Idioma original	Inglés
Páginas (desde-hasta)	1225-1242
Número de páginas	18
Publicación	Monatshefte fur Chemie
Volumen	135
N.º	10
DOI	https://doi.org/10.1007/s00706-004-0187-5
Estado	Publicada - oct. 2004
Publicado de forma externa	Sí

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10.1007/s00706-004-0187-5

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title = "Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design",

abstract = "Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent.",

keywords = "α-Hydroxy acids, α-Hydroxyacylamino acids, α-Mercapto acids, α-Mercaptoacylamino acids, 3-Hydroxysuccinimido sugars, Dielectrophiles, Glycosylamines, Maleimido sugars, N-Glycosylated depsipeptides",

author = "Christoph B{\"o}ttcher and Jan Spengler and Klaus Burger",

year = "2004",

month = oct,

doi = "10.1007/s00706-004-0187-5",

language = "Ingl{\'e}s",

volume = "135",

pages = "1225--1242",

journal = "Monatshefte fur Chemie",

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Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design. / Böttcher, Christoph; Spengler, Jan; Burger, Klaus.
En: Monatshefte fur Chemie, Vol. 135, N.º 10, 10.2004, p. 1225-1242.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

AU - Böttcher, Christoph

AU - Spengler, Jan

AU - Burger, Klaus

PY - 2004/10

Y1 - 2004/10

N2 - Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent.

AB - Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent.

KW - α-Hydroxy acids

KW - α-Hydroxyacylamino acids

KW - α-Mercapto acids

KW - α-Mercaptoacylamino acids

KW - 3-Hydroxysuccinimido sugars

KW - Dielectrophiles

KW - Glycosylamines

KW - Maleimido sugars

KW - N-Glycosylated depsipeptides

UR - https://www.scopus.com/pages/publications/7044260730

U2 - 10.1007/s00706-004-0187-5

DO - 10.1007/s00706-004-0187-5

M3 - Artículo

AN - SCOPUS:7044260730

SN - 0026-9247

VL - 135

SP - 1225

EP - 1242

JO - Monatshefte fur Chemie

JF - Monatshefte fur Chemie

IS - 10

ER -

Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

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