Patrón de tinción de anticuerpos antinucleares en pacientes con diagnóstico de enfermedades autoinmunes en Manabí, Ecuador

Objectives To detect the staining pattern of antinuclear antibodies (ANA) in patients with a presumptive diagnosis of autoimmune diseases (AID). Materials and Methods A study was carried out in 2507 patients referred to a private laboratory, who had ANA detected by the indirect immunofluorescence technique (IFI) taking into consideration ethical criteria. Results 743 patients (29.6 %) were positive. Regarding the characteristics of the popu-lations the female sex and age group 40 to 59 years were the most prevalent with 82.6% and 41.2 %, respectively, 44.8 % showed titers of 1/80 being the mottled pattern the most found with 47.2 % and the fine mottled sub-pattern with 35.7 %. Conclusions It is important to establish parameters associated with the diagnosis of EAI in various areas where precise data are not known, as well as other fortuitous findings in the presence of ANA positivity, also describing the characteristics of the popu-lation, patterns found and titers. The correlation of ANA with other pathologies such as SARS-CoV-2 infection and other agents of clinical importance is relevant.