Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Christoph Böttcher; Jan Spengler; Klaus Burger

doi:10.1007/s00706-004-0187-5

Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Christoph Böttcher
, Jan Spengler
, Klaus Burger

Leipzig University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac ₄-β-D-Glc-NH₂/Bzl₄-β-D-Glc-NH ₂ using hexafluoroacetone as protecting and activating reagent.

Original language	English
Pages (from-to)	1225-1242
Number of pages	18
Journal	Monatshefte fur Chemie
Volume	135
Issue number	10
DOIs	https://doi.org/10.1007/s00706-004-0187-5
State	Published - Oct 2004
Externally published	Yes

Keywords

α-Hydroxy acids
α-Hydroxyacylamino acids
α-Mercapto acids
α-Mercaptoacylamino acids
3-Hydroxysuccinimido sugars
Dielectrophiles
Glycosylamines
Maleimido sugars
N-Glycosylated depsipeptides

Access to Document

10.1007/s00706-004-0187-5

Cite this

@article{2b81901cbecf4b6a89b29d9270add06e,

title = "Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design",

abstract = "Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent.",

keywords = "α-Hydroxy acids, α-Hydroxyacylamino acids, α-Mercapto acids, α-Mercaptoacylamino acids, 3-Hydroxysuccinimido sugars, Dielectrophiles, Glycosylamines, Maleimido sugars, N-Glycosylated depsipeptides",

author = "Christoph B{\"o}ttcher and Jan Spengler and Klaus Burger",

year = "2004",

month = oct,

doi = "10.1007/s00706-004-0187-5",

language = "Ingl{\'e}s",

volume = "135",

pages = "1225--1242",

journal = "Monatshefte fur Chemie",

issn = "0026-9247",

number = "10",

}

TY - JOUR

T1 - Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

AU - Böttcher, Christoph

AU - Spengler, Jan

AU - Burger, Klaus

PY - 2004/10

Y1 - 2004/10

N2 - Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent.

AB - Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent.

KW - α-Hydroxy acids

KW - α-Hydroxyacylamino acids

KW - α-Mercapto acids

KW - α-Mercaptoacylamino acids

KW - 3-Hydroxysuccinimido sugars

KW - Dielectrophiles

KW - Glycosylamines

KW - Maleimido sugars

KW - N-Glycosylated depsipeptides

UR - https://www.scopus.com/pages/publications/7044260730

U2 - 10.1007/s00706-004-0187-5

DO - 10.1007/s00706-004-0187-5

M3 - Artículo

AN - SCOPUS:7044260730

SN - 0026-9247

VL - 135

SP - 1225

EP - 1242

JO - Monatshefte fur Chemie

JF - Monatshefte fur Chemie

IS - 10

ER -

Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this