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Hexafluoroacetone as a protecting and activating reagent. N- and O-glycosylation of isoserine and isocysteine *

  • Christoph Böttcher
  • , Jan Spengler
  • , Lothar Hennig
  • , Fernando Albericio
  • , Klaus Burger
  • Leipzig University
  • Institute for Research in Biomedicine

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Starting from HFA-protected malic and thiomalic acid a series of O- and N-glycoconjugates suitable for peptide and depsipeptide modification has been synthesized.

Original languageEnglish
Pages (from-to)577-595
Number of pages19
JournalMonatshefte fur Chemie
Volume136
Issue number4
DOIs
StatePublished - Apr 2005
Externally publishedYes

Keywords

  • Glycoconjugates
  • Glycosylamines
  • Hexafluoroacetone
  • Isocyanates
  • Malic acid
  • Thiomalic acid

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