Domino reactions with fluorinated five-membered heterocycles. α-Trifluoromethyl α-amino acids with unsaturated side-chains

K. Burger; L. Hennig; P. Tsouker; J. Spengler; F. Albericio; B. Koksch

doi:10.1007/s00726-006-0321-2

Domino reactions with fluorinated five-membered heterocycles. α-Trifluoromethyl α-amino acids with unsaturated side-chains

K. Burger
, L. Hennig
, P. Tsouker
, J. Spengler
, F. Albericio
, B. Koksch

Leipzig University
Institute for Research in Biomedicine
Free University of Berlin

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

α-Trifluoromethyl α-amino acids with unsaturated side-chains have been prepared from 5-fluoro-4-trifluoromethyloxazole and allyl, propargyl as well as terpene alcohols in a one-pot procedure.

Original language	English
Pages (from-to)	427-433
Number of pages	7
Journal	Amino Acids
Volume	31
Issue number	4
DOIs	https://doi.org/10.1007/s00726-006-0321-2
State	Published - Nov 2006
Externally published	Yes

Keywords

α-Trifluoromethyl α-amino acids
5-Fluoro-4-trifluoromethyloxazoles
Allyl alcohols
Claisen rearrangement
Farnesol
Geraniol
Nucleophilic aromatic substitution
Propargyl alcohols
Secondary structure

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10.1007/s00726-006-0321-2

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title = "Domino reactions with fluorinated five-membered heterocycles. α-Trifluoromethyl α-amino acids with unsaturated side-chains",

abstract = "α-Trifluoromethyl α-amino acids with unsaturated side-chains have been prepared from 5-fluoro-4-trifluoromethyloxazole and allyl, propargyl as well as terpene alcohols in a one-pot procedure.",

keywords = "α-Trifluoromethyl α-amino acids, 5-Fluoro-4-trifluoromethyloxazoles, Allyl alcohols, Claisen rearrangement, Farnesol, Geraniol, Nucleophilic aromatic substitution, Propargyl alcohols, Secondary structure",

author = "K. Burger and L. Hennig and P. Tsouker and J. Spengler and F. Albericio and B. Koksch",

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doi = "10.1007/s00726-006-0321-2",

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journal = "Amino Acids",

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T1 - Domino reactions with fluorinated five-membered heterocycles. α-Trifluoromethyl α-amino acids with unsaturated side-chains

AU - Burger, K.

AU - Hennig, L.

AU - Tsouker, P.

AU - Spengler, J.

AU - Albericio, F.

AU - Koksch, B.

PY - 2006/11

Y1 - 2006/11

N2 - α-Trifluoromethyl α-amino acids with unsaturated side-chains have been prepared from 5-fluoro-4-trifluoromethyloxazole and allyl, propargyl as well as terpene alcohols in a one-pot procedure.

AB - α-Trifluoromethyl α-amino acids with unsaturated side-chains have been prepared from 5-fluoro-4-trifluoromethyloxazole and allyl, propargyl as well as terpene alcohols in a one-pot procedure.

KW - α-Trifluoromethyl α-amino acids

KW - 5-Fluoro-4-trifluoromethyloxazoles

KW - Allyl alcohols

KW - Claisen rearrangement

KW - Farnesol

KW - Geraniol

KW - Nucleophilic aromatic substitution

KW - Propargyl alcohols

KW - Secondary structure

UR - https://www.scopus.com/pages/publications/33845191095

U2 - 10.1007/s00726-006-0321-2

DO - 10.1007/s00726-006-0321-2

M3 - Artículo

C2 - 16715414

AN - SCOPUS:33845191095

SN - 0939-4451

VL - 31

SP - 427

EP - 433

JO - Amino Acids

JF - Amino Acids

IS - 4

ER -

Domino reactions with fluorinated five-membered heterocycles. α-Trifluoromethyl α-amino acids with unsaturated side-chains

Abstract

Keywords

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